Tag Archives: lsd






Guitarist and songwriter Jerry Garcia was the frontman of the psychedelic rock band the Grateful Dead. He also worked on a number of collaborations and solo albums. He is well-known for his distinctive guitar playing and for his band’s “Deadheads,” fans who followed the band from concert to concert. Garcia struggled with heroin addiction. He died of a heart attack in 1995.



“I don’t go onstage with some kind of messianic vision or anything. I’m basically going out there hoping my guitar is in tune.”

– Jerry Garcia


Band leader, guitarist, and songwriter. Born on August 1, 1942, in San Francisco, California. Garcia was the son of a Spanish immigrant who grew up to become a bandleader popular in the San Francisco area. He studied piano as a boy but turned to the guitar in his teens. He dropped out of school at age 17 and served nine months in the U.S. Army before being discharged for poor conduct. He began to play folk and blues guitar, alone or with pickup groups, in clubs in the San Francisco area while working as a salesman and music teacher in a music store.

In 1965 he formed a band, the Warlocks, but on discovering another group with that name, it was changed to the Grateful Dead (1966). Closely involved with the San Francisco hippie movement and the use of drugs such as LSD, the band first played “psychedelic” rock but moved on to a more diverse repertory of rock styles in the 1970s. From around 1974 the band’s members began to go their own ways, and Garcia made solo appearances and albums. In the 1980s he became heavily addicted to drugs, and after being arrested in 1985 was sent to a treatment center. After emerging from a diabetic coma, he decided to turn his life around, and the band made a comeback (1987) with a hit single, “Touch of Gray” and an album, In the Dark.

Garcia and the rest of the band enjoyed this new wave of success and continued to tour, drawing legions of fans – new and old – to their shows. The Grateful Dead had built quite a following over the years and their loyal fans, sometimes called “Deadheads,” were known to travel around the country to catch their concerts. Unfortunately, the show could not go on forever. Despite Garcia’s efforts to improve his lifestyle, all of the years of hard living caught up with him. He died of heart failure on August 9, 1995, in Forest Knolls, California.

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Hofmann’s discovery of the effect of LSD in Basel came 5 years after his original synthesis of the molecule in 1938. LSD-25, as it was called then, was synthesized and tried on animals. No interesting effects appeared, and the molecule was consigned to the “useless” heap. If it had stayed there, the state of today’s world would be different.

By the end of November, 1942, scientists in an underground lab at the University of Chicago were ready to test the hypothesis that Enrico Fermi’s method of slowing the emission of neutrons from a pile of uranium was safe. They could produce a chain reaction that would not gallop out of control and set the world on fire, they reckoned. On December 2 the instruments to measure the reaction were in place. The pile went active.

A cheer went up. Leo Szilard, one of the physicists present, had gone out that morning and bought a bottle of wine and some paper cups in case the experiment succeeded. When it did, and it was time to celebrate, Szilard offered a toast. “This will go down as a black day in the history of mankind,” he said.

130 days later, or 131 or 132 – Hofmann is not sure – the chemist in the old Sandoz lab (since demolished – see photo) had what he called a “Vorgefühl.” The usual English word for this is “presentiment,” but the German word suggests something stronger than the laid-back “presentiment.” Something was telling Hofmann to retrace his steps and perform a new synthesis of the discarded molecule, LSD-25. It had to be that molecule and not one of the others consigned to the “useless” pile.

(The first photo below shows the equipment Hofmann used.) The second synthesis was completed on April 16. Accidentally, Hofmann breathed in or swallowed some of the material, and had the merit to realize, when its effect came upon him, that something of momentous significance had happened. He assumed LSD was the cause, and waited until the next working day, a Monday, to try again. The assumption proved right, and a new chapter of history opened.

Soon, the directors of Sandoz Pharmaceuticals were trying LSD, and a research project under W.A. Stoll, psychiatrist and nephew of one of the Sandoz directors, took shape. Those must have been exciting days. More than 40 subjects, the majority busy, working people, participated.

Hofmann does not remember what he was doing when the “presentiment” came over him. He won’t say if it came in a dream, or if he was in a state of unusual lucidity.  One is free to speculate that the “instruction” to re-synthesize LSD came from a spiritual power which intervenes in the affairs of man to restore order when the danger of disorder has become too great. The reckless act of science in Chicago in December, 1942 was remedied in Basel four months later, with Albert Hofmann chosen as the instrument to perform the cure.

Old Sandoz Laboratory

 Old Sandoz Laboratory, Since Demolished

LSD Brominator

 Equipment for the Bromination of LSD in Dr. Hofmann’s Laboratory